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BI8626 induces HUWE1 ectopically expresses to abolishe ubiquitination of MCL1 in HeLa cells
InChiKey: MVESGEUGPWQJCZ-WFGJKAKNSA-N
1021/jp909327y
this is not significant
11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido]ethanesulfonyl}oxidanium
YM-53601 ra B inhibitor 1 BI8626 induces HUWE1 ectopically expressesYM 53601 is an inhibitor of squalene synthase activity that acts by lowering cholesterol as well as triglycerides. YM 53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo. YM 53601 inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid lowering agent. YM 53601 is also an inhibitor of farnesyl diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV
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